Kidney Disorders, Chronic

Jun 15, 2019 Issue
Diabetic Kidney Disease: Diagnosis, Treatment, and Prevention [Article]

Diabetic kidney disease (DKD) is associated with higher cardiovascular and all-cause morbidity and mortality. Screening is best done with annual spot urine albumin/creatinine ratio testing. Treatment includes management of hyperglycemia, hypertension, hyperlipidemia, and cessation of tobacco use. Blood pressure should be monitored. Several medications may help prevent or slow progression of DKD. Patients who progress to at least stage 3 DKD may benefit from referral to nephrology subspecialists.

Apr 1, 2019 Issue
Direct Oral Anticoagulants vs. Warfarin to Prevent Stroke and Embolic Events in Patients with Atrial Fibrillation and CKD [Cochrane for Clinicians]

Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for the use of direct oral a...

Dec 15, 2017 Issue
Chronic Kidney Disease: Detection and Evaluation [Article]

Get the latest recommendations on screening, assessment, and management of chronic kidney disease, and find out which indications should prompt consideration of referral to a nephrologist.

Apr 1, 2017 Issue
Effects of Altered Dietary Salt Intake in Patients with Chronic Kidney Disease [Cochrane for Clinicians]

Reducing salt intake lowers blood pressure and reduces proteinuria in patients with CKD, but there is no evidence to determine whether lowering salt consumption leads to clinically significant reductions in end-stage renal disease, cardiovascular events, or all-cause mortality.

Mar 15, 2016 Issue
Diagnosis and Management of Nephrotic Syndrome in Adults [Article]

The diagnosis of nephrotic syndrome is based on typical clinical features, with confirmation of heavy proteinuria and hypoalbuminemia. Despite the lack of evidence-based guidelines, several treatment options are commonly used to manage the condition.

Jul 15, 2014 Issue
ACP Releases Guideline on Screening, Monitoring, and Treatment of Stage 1 to 3 Chronic Kidney Disease [Practice Guidelines]

Based on a systematic evidence review, this guideline from the American College of Physicians (ACP) presents recommendations on screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease in adults.

Apr 1, 2014 Issue
No Benefit to Addition of Stenting for Treatment of Atherosclerotic Renal Artery Stenosis [POEMs]

In patients with severe atherosclerotic renal artery stenosis and hypertension or chronic kidney disease, renal artery stenting does not provide an additional benefit when added to comprehensive medical therapy that includes blood pressure and diabetes mellitus management, and antiplatelet and lipid therapies.

Feb 15, 2014 Issue
Screening for Chronic Kidney Disease: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to assess the balance of benefits and harms of routine screening for chronic kidney disease (CKD) in asymptomatic adults.

Feb 15, 2014 Issue
Screening for Chronic Kidney Disease [Putting Prevention into Practice]

A 55-year-old woman with no history of diabetes mellitus or hypertension asks to be screened for chronic kidney disease (CKD). Her 88-year-old mother has end-stage renal disease and is currently undergoing renal dialysis. The patient says she wants to take all necessary precautions to prevent this from happening to her.

Oct 15, 2012 Issue
Update on the Management of Chronic Kidney Disease [Article]

Chronic kidney disease is common and associated with significant morbidity. Given the high risk of cardiovascular morbidity and mortality in patients with chronic kidney disease, it is important to identify and treat related risk factors. However, there is growing uncertainty about the benefits of ...

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