Kidney Disorders, Chronic

May 01, 2022 Issue
Reduced Dietary Salt for Patients With Chronic Kidney Disease [Cochrane for Clinicians]

In patients with chronic kidney disease (CKD), reducing dietary salt intake by approximately 4.2 g per day lowers mean systolic blood pressure by 6.9 mm Hg and diastolic blood pressure by 3.9 mm Hg compared with patients on a higher salt diet. In patients with CKD who do not have end-stage renal dis...

Nov 01, 2021 Issue
End-Stage Renal Disease: Medical Management [Article]

End-stage renal disease (ESRD) is diagnosed when kidney function is no longer adequate for long-term survival without kidney transplantation or dialysis. Primary care clinicians should refer people at risk of ESRD to nephrology to optimize disease management. Kidney transplantation typically yields ...

Jun 1, 2021 Issue
Chronic Kidney Disease in Diabetes: Guidelines from KDIGO [Practice Guidelines]

The Kidney Disease: Improving Global Outcomes (KDIGO) group, an international organization dedicated to nephrology clinical practice guidelines, has developed a new guideline for management of diabetes with chronic kidney disease.

Dec 1, 2020 Issue
Low-Protein Diets for Adults Without Diabetes Mellitus Who Have CKD [Cochrane for Clinicians]

In patients without diabetes mellitus who have chronic kidney disease, is a low-protein diet effective at preventing progression to end-stage renal disease or the need for dialysis?

Sep 15, 2020 Issue
Chronic Kidney Disease: Evaluation and Treatment Guidelines from the VA/DoD [Practice Guidelines]

The U.S. Department of Veterans Affairs and Department of Defense have updated recommendations for evaluation and treatment of chronic kidney disease.

Jun 15, 2019 Issue
Diabetic Kidney Disease: Diagnosis, Treatment, and Prevention [Article]

Diabetic kidney disease (DKD) is associated with higher cardiovascular and all-cause morbidity and mortality. Screening is best done with annual spot urine albumin/creatinine ratio testing. Treatment includes management of hyperglycemia, hypertension, hyperlipidemia, and cessation of tobacco use. Blood pressure should be monitored. Several medications may help prevent or slow progression of DKD. Patients who progress to at least stage 3 DKD may benefit from referral to nephrology subspecialists.

Apr 1, 2019 Issue
Direct Oral Anticoagulants vs. Warfarin to Prevent Stroke and Embolic Events in Patients with Atrial Fibrillation and CKD [Cochrane for Clinicians]

Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for the use of direct oral a...

Dec 15, 2017 Issue
Chronic Kidney Disease: Detection and Evaluation [Article]

Get the latest recommendations on screening, assessment, and management of chronic kidney disease, and find out which indications should prompt consideration of referral to a nephrologist.

Apr 1, 2017 Issue
Effects of Altered Dietary Salt Intake in Patients with Chronic Kidney Disease [Cochrane for Clinicians]

Reducing salt intake lowers blood pressure and reduces proteinuria in patients with CKD, but there is no evidence to determine whether lowering salt consumption leads to clinically significant reductions in end-stage renal disease, cardiovascular events, or all-cause mortality.

Mar 15, 2016 Issue
Diagnosis and Management of Nephrotic Syndrome in Adults [Article]

The diagnosis of nephrotic syndrome is based on typical clinical features, with confirmation of heavy proteinuria and hypoalbuminemia. Despite the lack of evidence-based guidelines, several treatment options are commonly used to manage the condition.

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