Kidney Disorders, Chronic

Apr 1, 2014 Issue
No Benefit to Addition of Stenting for Treatment of Atherosclerotic Renal Artery Stenosis [POEMs]

In patients with severe atherosclerotic renal artery stenosis and hypertension or chronic kidney disease, renal artery stenting does not provide an additional benefit when added to comprehensive medical therapy that includes blood pressure and diabetes mellitus management, and antiplatelet and lipid therapies.

Feb 15, 2014 Issue
Screening for Chronic Kidney Disease: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to assess the balance of benefits and harms of routine screening for chronic kidney disease (CKD) in asymptomatic adults.

Feb 15, 2014 Issue
Screening for Chronic Kidney Disease [Putting Prevention into Practice]

A 55-year-old woman with no history of diabetes mellitus or hypertension asks to be screened for chronic kidney disease (CKD). Her 88-year-old mother has end-stage renal disease and is currently undergoing renal dialysis. The patient says she wants to take all necessary precautions to prevent this from happening to her.

Oct 15, 2012 Issue
Update on the Management of Chronic Kidney Disease [Article]

Chronic kidney disease is common and associated with significant morbidity. Given the high risk of cardiovascular morbidity and mortality in patients with chronic kidney disease, it is important to identify and treat related risk factors. However, there is growing uncertainty about the benefits of ...

Apr 1, 2012 Issue
End-Stage Renal Disease: Symptom Management and Advance Care Planning [Article]

The prevalence of end-stage renal disease continues to increase, and dialysis is offered to older and more medically complex patients. Pain is problematic in up to one-half of patients receiving dialysis and may result from renal and nonrenal etiologies. Opioids can be prescribed safely, but the pat...

Nov 15, 2011 Issue
Chronic Kidney Disease: Detection and Evaluation [Article]

Chronic kidney disease affects an estimated 27 million adults in the United States, and is associated with significantly increased risk of cardiovascular disease and stroke. Patients should be assessed annually to determine whether they are at increased risk of developing chronic kidney disease base...

Jan 1, 2010 Issue
Statins for Non-Dialysis Chronic Kidney Disease [Cochrane for Clinicians]

When taken over a five-year period, statins significantly reduce all-cause mortality (number needed to treat [NNT] = 56), cardiovascular mortality (NNT = 86), and nonfatal cardiovascular events (NNT = 25).

Jul 1, 2007 Issue
ACE Inhibitors vs. ARBs for Patients with Diabetic Kidney Disease [Cochrane for Clinicians]

Studies comparing ACE inhibitors or ARBs with placebo found no mortality benefit in patients with diabetic kidney disease. A subgroup analysis of five studies (2,034 total patients) found that, when given at full or maximally tolerated doses, ACE inhibitors reduce all-cause mortality (relative risk ...

May 15, 2007 Issue
Drug Dosing Adjustments in Patients with Chronic Kidney Disease [Article]

Chronic kidney disease affects renal drug elimination and other pharmacokinetic processes involved in drug disposition (e.g., absorption, drug distribution, nonrenal clearance [metabolism]). Drug dosing errors are common in patients with renal impairment and can cause adverse effects and poor outcom...

Jan 15, 2007 Issue
Chronic Kidney Disease Screening Recommended in Patients with CVD [Practice Guidelines]

The American Heart Association (AHA) published recommendations for the detection of chronic kidney disease in patients with cardiovascular disease (CVD). Chronic kidney disease is common in patients with CVD; moreover, it also is a risk factor for developing CVD.

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