Dec 1, 2016 Issue
Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis [Article]

Blood tests, imaging, and biopsy can assist in narrowing down the differential diagnosis of lymphadenopathy without a clear etiology, depending on multiple factors, such as location of the abnormality.

May 15, 2015 Issue
Evaluation of Neck Masses in Adults [Article]

Etiologies of a neck mass can be grouped according to whether the mass is acute, subacute, or chronic. Find out how to further narrow the diagnosis.

Mar 1, 2014 Issue
Evaluation and Management of Neck Masses in Children [Article]

Neck masses in children usually fall into one of three categories: developmental, inflammatory/reactive, or neoplastic. Common congenital developmental masses in the neck include thyroglossal duct cysts, branchial cleft cysts, dermoid cysts, vascular malformations, and hemangiomas. Inflammatory neck...

Jan 15, 2011 Issue
Cat-scratch Disease [Article]

Cat-scratch disease is a common infection that usually presents as tender lymphadenopathy. It should be included in the differential diagnosis of fever of unknown origin and any lymphadenopathy syndrome. Asymptomatic, bactere- mic cats with Bartonella henselae in their saliva serve as vectors by bit...

Sep 1, 2008 Issue
Bilateral Lower Extremity Edema [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Oct 15, 2005 Issue
Hidradenitis Suppurativa: A Treatment Challenge [Article]

Hidradenitis suppurativa is a chronic, recurrent, debilitating disease that presents with painful, inflamed lesions in the apocrine-gland-bearing areas of the body, most commonly the axillary, inguinal, and anogenital areas. Etiology traditionally has been attributed to occlusion of the apocrine duc...

Dec 1, 2002 Issue
Lymphadenopathy and Malignancy [Article]

The majority of patients presenting with peripheral lymphadenopathy have easily identifiable causes that are benign or self-limited. Among primary care patients presenting with lymphadenopathy, the prevalence of malignancy has been estimated to be as low as 1.1 percent. The critical challenge for th...

Sep 1, 2002 Issue
The Adult Neck Mass [Article]

Family physicians frequently encounter neck masses in adult patients. A careful medical history should be obtained, and a thorough physical examination should be performed. The patient's age and the location, size, and duration of the mass are important pieces of information. Inflammatory and infect...

Oct 15, 1998 Issue
Lymphadenopathy: Differential Diagnosis and Evaluation [Article]

Although the finding of lymphadenopathy sometimes raises fears about serious illness, it is, in patients seen in primary care settings, usually a result of benign infectious causes. Most patients can be diagnosed on the basis of a careful history and physical examination. Localized adenopathy should...

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