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Menstrual Disorders

Aug 01, 2021 Issue
Dysmenorrhea [Article]

Dysmenorrhea is common and usually independent of, rather than secondary to, pelvic pathology. Dysmenorrhea occurs in 50% to 90% of adolescent girls and women of reproductive age and is a leading cause of absenteeism. Secondary dysmenorrhea as a result of endometriosis, pelvic anatomic abnormalities...


Aug 01, 2021 Issue
Levonorgestrel-Releasing Intrauterine System for Reducing Heavy Menstrual Bleeding [Cochrane for Clinicians]

The levonorgestrel-releasing intrauterine system is more effective than other medical therapies at reducing menstrual bleeding volume, with similar rates of adverse effects. The effectiveness of the levonorgestrel-releasing intrauterine system compared with endometrial ablation and hysterectomy has been inadequately studied.


May 1, 2021 Issue
Exercise for Dysmenorrhea [Cochrane for Clinicians]

Low-intensity exercise, such as stretching or core strengthening, and high-intensity exercise, such as Zumba or aerobic training, improve menstrual pain intensity compared with no exercise.


Apr 15, 2021 Issue
Elagolix, Estradiol, and Norethindrone Kit (Oriahnn) for the Management of Heavy Menstrual Bleeding Associated with Fibroids [STEPS]

Oriahnn can decrease menstrual blood loss in premenopausal patients with uterine fibroids. Although it has been studied for only six months of use and may result in significant bone loss, it is labeled for up to two years of continuous therapy.


Aug 1, 2020 Issue
Heavy Menstrual Bleeding in Premenopausal Patients and the Role of NSAIDs [Cochrane for Clinicians]

NSAIDs are effective for reducing heavy menstrual bleeding in premenopausal patients with menorrhagia when compared with placebo.


May 15, 2020 Issue
Heavy Menstrual Bleeding in Adolescents: ACOG Management Recommendations [Practice Guidelines]

The American College of Obstetricians and Gynecologists (ACOG) has new recommendations and conclusions about menstrual bleeding disorders in adolescents.


Dec 1, 2019 Issue
Combined Hormonal Contraceptives for Heavy Menstrual Bleeding [Cochrane for Clinicians]

Combined oral contraceptives decrease the number of women reporting menorrhagia over six months compared with placebo (absolute risk reduction = 36.7%; number needed to treat = 2.7).


Jul 1, 2019 Issue
Amenorrhea: A Systematic Approach to Diagnosis and Management [Article]

Many underlying conditions can lead to amenorrhea. Primary amenorrhea is the failure to reach menarche. Secondary amenorrhea is the cessation of regular menses for three months or the cessastion of irregular menses for six months. Pregnancy should be excluded in all cases, as well as an evaluation that includes a history, physical examination, and laboratory assessment of serum hormone levels. Treatment should address the underlying cause.


Jul 1, 2017 Issue
Surgery vs. Medical Therapy for Heavy Menstrual Bleeding [Cochrane for Clinicians]

In women of reproductive age with chronic heavy menstrual bleeding, hysterectomy is the most effective treatment for controlling symptoms. Conservative surgery is more effective for controlling bleeding symptoms at one and two years than oral medications or the levonorgestrel-releasing intrauterine system, but by five years there is no difference.


Aug 1, 2016 Issue
Premenstrual Syndrome and Premenstrual Dysphoric Disorder [Article]

Get the latest diagnostic criteria for premenstrual syndrome and premenstrual dysphoric disorder, and find out which treatments have the best evidence of effectiveness.


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