Jan 15, 2008 Issue
Dietary Supplements for Osteoarthritis [Article]

A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not...

Apr 1, 2006 Issue
Glucosamine Treatment for Osteoarthritis [Cochrane for Clinicians]

This review shows that, compared with placebo, glucosamine sulfate produces a moderate, clinically significant reduction in pain and improvement in function for patients with osteoarthritis. However, study results were not consistent. Most studies in the review used preparations of glucosamine sulfa...

Oct 1, 2005 Issue
Intra-articular Corticosteroid for Treating Osteoarthritis of the Knee [Cochrane for Clinicians]

An injection of the knee joint with a corticosteroid may improve the patient’s symptoms for up to three weeks after the injection (number needed to treat [NNT]= 3 to 4). There is no evidence that this intervention improves function, and there is little evidence of the benefits persisting beyond thre...

Sep 1, 2004 Issue
Effect of Exercise Intensity on Osteoarthritis [Cochrane for Clinicians]

Although land-based exercise improves physical function, there is no evidence that high-intensity cycling offers benefits over low-intensity cycling for patients with osteoarthritis of the knee.

Jan 15, 2003 Issue
Alternative Therapies for Traditional Disease States: Osteoarthritis [Article]

Americans spend more on natural remedies for osteoarthritis than for any other medical condition. In treating osteoarthritis, glucosamine and chondroitin sulfate, two of the molecular building blocks found in articular cartilage, are the most commonly used alternative supplements. In randomized tria...

Mar 1, 2002 Issue
Osteoarthritis: Diagnosis and Therapeutic Considerations [Article]

Osteoarthritis is a common rheumatologic disorder. It is estimated that 40 million Americans and 70 to 90 percent of persons older than 75 years are affected by osteoarthritis. Although symptoms of osteoarthritis occur earlier in women, the prevalence among men and women is equal. In addition to age...

Jul 15, 2001 Issue
Radiographic Assessment of Osteoarthritis [Article]

Osteoarthritis is one of the most prevalent and disabling chronic conditions affecting older adults and a significant public health problem among adults of working age. As the bulk of the U.S. population ages, the prevalence of osteoarthritis is expected to rise. Although the incidence of osteoarthr...

Aug 1, 2000 Issue
Intra-articular Hyaluronic Acid Injections for Knee Osteoarthritis [Article]

Knee osteoarthritis is a common but often difficult problem to manage in primary care. Traditional nonsurgical management, consisting of lifestyle modification, physical therapy and pharmacologic therapy (e.g., analgesics, anti-inflammatory medications), is often ineffective or leaves residual sympt...

Mar 15, 2000 Issue
Osteoarthritis: Current Concepts in Diagnosis and Management [Article]

Most patients with osteoarthritis seek medical attention because of pain. The safest initial approach is to use a simple oral analgesic such as acetaminophen (perhaps in conjunction with topical therapy). If pain relief is inadequate, oral nonsteroidal anti-inflammatory drugs or intra-articular inje...

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