Parkinson Disease

Dec 1, 2020 Issue
Parkinson Disease [Article]

Parkinson disease is a progressive neurodegenerative disorder with significant morbidity and mortality. The diagnosis of Parkinson disease is clinical, and key disease features are bradykinesia, rigidity, and tremor. Parkinson disease progression is variable and clinical signs cannot be used to predict progression accurately. Interdisciplinary team care can alleviate multiple symptoms of Parkinson disease.

Oct 1, 2015 Issue
A Family Physician Confronts Parkinson Disease [Close-ups]

Education about promising physical therapies and treatments that may be on the horizon can be a source of encouragement for physicians and patients alike when facing a diagnosis of Parkinson disease.

Feb 15, 2013 Issue
Parkinson Disease: An Update [Article]

Parkinson disease is a progressive neurologic disorder afflicting approximately 1 percent of Americans older than 60 years. The cardinal features of Parkinson disease are bradykinesia, rigidity, tremor, and postural instability. There are a number of neurologic conditions that mimic the disease, ma...

Jul 1, 2009 Issue
Dopamine Agonists for Early Parkinson Disease [Cochrane for Clinicians]

Dopamine agonists, such as pramipexole (Mirapex), ropinirole (Requip), pergolide (formerly Permax), and apomorphine (Apokyn), improve the motor fluctuations and dyskinesias that commonly occur with levodopa, but at the expense of increasing nonmotor adverse effects and noncompliance. An individual, case-based approach should be employed.

Apr 1, 2007 Issue
Parkinson's Disease [Clinical Evidence Handbook]

What are the effects of drug treatments in persons with early stage Parkinson's disease? What are the effects of adding other treatments in persons with motor complications from levodopa? What are the effects of surgery and nursing and rehabilitation treatments in persons with Parkinson's disease?

Mar 15, 2007 Issue
AAN Releases Recommendations on Treatment of Parkinson's Disease [Practice Guidelines]

Recommendations from the Quality Standards Subcommittee of the American Academy of Neurology (AAN) discuss aspects and treatment of Parkinson's disease. This condition is the second most common neurodegenerative disease and is characterized by bradykinesia; tremor at rest; rigidity; and abnormalities of balance, posture, and gait.

Dec 15, 2006 Issue
Parkinson's Disease: Diagnosis and Treatment [Article]

Parkinson's disease is a common neurodegenerative disorder that can cause significant disability and decreased quality of life. The cardinal physical signs of the disease are distal resting tremor, rigidity, bradykinesia, and asymmetric onset. Levodopa is the primary treatment for Parkinson's diseas...

Apr 15, 1999 Issue
Update on Parkinson's Disease [Article]

Parkinson's disease is a progressive degenerative disorder of the central nervous system. The hallmark physical signs are tremor, rigidity and bradykinesia. Idiopathic Parkinson's disease is caused by the progressive loss of dopaminergic neurons in the substantia nigra and nigrostriatal pathway of t...

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