Seizure Disorders

May 01, 2022 Issue
Evaluation After a First Seizure in Adults [Article]

Seizures are transient signs and symptoms of abnormal, excessive, or synchronous neuronal activity in the brain. Up to 10% of adults have a seizure during their lifetime, with increasing incidence in people older than 55 years. One-third of people have a recurrent seizure within one year of an initi...

May 1, 2021 Issue
Ketogenic Diets for Drug-Resistant Epilepsy [Cochrane for Clinicians]

In children with drug-resistant epilepsy, a ketogenic diet decreases the risk of seizures by 50% after three to four months.

Apr 1, 2019 Issue
Febrile Seizures: Risks, Evaluation, and Prognosis [Article]

Children who have a simple febrile seizure and are well-appearing usually do not require routine diagnostic testing. For children with complex seizures, the neurologic examination should guide further evaluation. given the benign nature of febrile seizures, the routine use of antiepileptics is not indicated because of adverse effects of these medications. Antipyretics do not decrease the risk of febrile seizures. Management consists of parent reassurance and education regarding home management of seizures.

May 1, 2018 Issue
Antiepileptic Drug Monotherapy for Epilepsy [Cochrane for Clinicians]

In patients with partial-onset (focal) seizures, levetiracetam (Keppra), lamotrigine (Lamictal), and carbamazepine (Tegretol) were associated with the longest time to treatment withdrawal (i.e., the recommended patient-oriented outcome measure that balances tolerability with effectiveness).

Jul 15, 2017 Issue
Epilepsy: Treatment Options [Article]

Routinely initiating treatment with an antiepileptic after a first seizure is not recommended in part because of the potential for adverse effects. Identifying when patients will benefit from pharmacotherapy or other adjunctive options requires ongoing careful assessment of risk factors.

Feb 1, 2017 Issue
Antiepileptic Drugs After First Unprovoked Seizure [Medicine by the Numbers]

The decision to start an antiepileptic drug after a first unprovoked seizure has long been a clinically challenging one.

Jun 1, 2016 Issue
When to Discontinue Antiepileptic Drug Therapy for Patients in Remission [Cochrane for Clinicians]

Children with epilepsy should be seizure-free for at least two years before stopping antiepileptic drug therapy, especially those who have partial seizures or a history of abnormal electroencephalography (EEG) results.

Nov 1, 2015 Issue
Unprovoked First Seizures in Adults: Management Recommendations from the AAN [Practice Guidelines]

This guideline from the Academy of Neurology (AAN) provides information on prognosis and management options for unprovoked first seizures in adults.

Jan 15, 2015 Issue
Absence Seizures in Children [Clinical Evidence Handbook]

What are the effects of treatments for typical absence seizures in children?

Aug 15, 2012 Issue
Evaluation of First Nonfebrile Seizures [Article]

Nonfebrile seizures may indicate underlying disease or epilepsy. The patient history can often distinguish epileptic seizures from nonepileptic disorders by identifying the events directly preceding the convulsion, associated conditions, and details of the seizure, including triggers, length, and ty...

Pages: 1 2 3 Next

Email Alerts

Don't miss a single issue. Sign up for the free AFP email table of contents.

Sign Up Now