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Skin Conditions

Sep 15, 2018 Issue
Crisaborole (Eucrisa) for Mild to Moderate Atopic Dermatitis [STEPS]

Crisaborole has been shown to be effective in about one-third of patients who use it, but it is much more expensive than other available products. Although crisaborole is a safe option for patients in whom topical corticosteroids are considered risky (e.g., children at least two years of age), it sh...


Sep 1, 2018 Issue
Annular Lesions: Diagnosis and Treatment [Article]

Many diseases present with cutaneous annular lesions, making distinction by physical appearance alone challenging. Find out which clinical clues can help diagnose common and uncommon diseases associated with annular lesions.


Jul 15, 2018 Issue
Lower Extremity Erythema [Photo Quiz]

A man who lived a hermit lifestyle presented with an open eschar over the left medial malleolus.


Jun 15, 2018 Issue
Oxymetazoline Hydrochloride 1% Cream (Rhofade) for Persistent Facial Erythema Associated with Rosacea [STEPS]

Oxymetazoline cream has been shown to be safe and effective at reducing erythema in a small portion of treated patients, but research showing its effectiveness relative to other options is lacking.


Jun 1, 2018 Issue
Hyperhidrosis: Management Options [Article]

Excessive sweating can impair patients’ quality of life, causing embarrassment in work and social settings. A variety of therapies are available for treating hyperhidrosis of the axillae, palms, soles, and face. Review common first- and second-line treatment options, such as topical aluminum chloride, botulinum toxin injections, and iontophoresis, as well as procedures for more severe cases.


May 1, 2018 Issue
Hyperpigmented Patches on the Dorsal Hands [Photo Quiz]

A man with a history of HIV infection, diabetes, alcohol use disorder, and tobacco use disorder presented with skin lesions on his upper extremities and hyperpigmented patches on his face.


Jan 15, 2018 Issue
Abrupt Onset of a Tender Rash on the Upper and Lower Extremities [Photo Quiz]


Jan 15, 2018 Issue
Noninfectious Penile Lesions [Article]

Predominant characteristics of a lesion can be accounted for with a thorough genitourinary examination. Knowing the distinguishing features of the four noninfectious types of lesions, and which forms are likely to mimic others, is essential for efficient diagnosis and treatment.


Jan 1, 2018 Issue
Pityriasis Rosea: Diagnosis and Treatment [Article]

Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch and progresses to a generalized rash over the trunk and limbs. Learn how to differentiate pityriasis rosea from other skin conditions, and get the latest evidence on the most effective treatments.


Jan 1, 2018 Issue
Effectiveness of Moisturizers in the Treatment of Patients with Eczema [Cochrane for Clinicians]

Moisturizers decrease the rate of eczema flare-ups by 3.7 times vs. no treatment (number needed to treat [NNT] = 4), as well as the amount of topical corticosteroids used per eczema flare-up (9.3 g less). Adverse effects are minimal.


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