Oct 1, 2017 Issue
Recurrent Ischemic Stroke: Strategies for Prevention [Article]

Antiplatelet therapy, such as aspirin, clopidogrel, and aspirin/dipyridamole, is recommended to reduce the risk of recurrence after an initial stroke. Controlling risk factors and implementing lifestyle modifications, including smoking cessation, reducing alcohol intake, and increasing physical activity, are also important.

Jun 1, 2017 Issue
Physical Fitness Training for Patients with Stroke [Cochrane for Clinicians]

There is moderate-quality evidence that physical fitness training improves disability after stroke. Cardiovascular training that includes only aerobic exercise has a moderate effect on disability (standard mean difference [SMD] = 0.52 on a pooled disability scale), although it is not clear whether t...

Nov 1, 2016 Issue
The Risk of MI and Ischemic Stroke with Combined Oral Contraceptives [Cochrane for Clinicians]

The overall risk of MI and ischemic stroke is increased in women who use combined oral contraceptives. The relative risk of MI and ischemic stroke increases as estrogen dose rises, increasing by 60% with doses of 20 mcg and more than doubling when doses of 50 mcg or more are used.

Aug 15, 2016 Issue
Pioglitazone After Stroke or TIA Reduces Stroke and MI, but Also Has Significant Harms [POEMs]

In patients with a recent stroke or TIA and evidence of insulin resistance, pioglitazone reduces the likelihood of myocardial infarction (MI) or stroke (number needed to treat [NNT] = 36 over five years) but increases the risk of significant weight gain (number needed to treat to harm [NNTH] =14), edema (NNTH = 9), and fracture (NNTH = 53).

Jul 1, 2015 Issue
CEA vs. Stenting: Mixed Results, Mostly Bad [POEMs]

These two randomized trials, one with short-term outcomes and the other with five-year outcomes, demonstrate that carotid artery stenting results in more frequent strokes (clinical and radiographically detected) than carotid endarterectomy (CEA). However, the rate of fatal and disabling strokes is comparable.

May 15, 2015 Issue
Screening for Carotid Artery Stenosis [Putting Prevention into Practice]

N.C. is a 65-year-old woman who presents for her yearly checkup. She walks one to two miles daily, is in generally good health, has no significant cardiovascular history, and has no health concerns at today's visit.

May 15, 2015 Issue
Screening for Asymptomatic Carotid Artery Stenosis: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF recommends against screening for asymptomatic carotid artery stenosis in the general adult population.

Apr 15, 2015 Issue
Diagnosis of Acute Stroke [Article]

Review the most common stroke symptoms and mimics, how to distinguish between ischemic and hemorrhagic stroke, and which diagnostic tests and imaging techniques to employ. Learn how to evaluate stroke severity to determine the need for thrombolytic therapy, and how to educate patients on the warning signs of stroke.

Mar 1, 2015 Issue
AHA/ASA Release Guideline on Stroke Prevention in Women [Practice Guidelines]

The American Heart Association and American Stroke Association (AHA/ASA) have released a guideline to help physicians identify women with increased risk of stroke and initiate appropriate preventive measures. The guideline includes recommendations on pregnancy and stroke; cerebral venous thrombosis;...

Jan 15, 2015 Issue
AHA and ASA Release Guideline for Prevention of Future Stroke in Patients with Stroke or TIA [Practice Guidelines]

The American Heart Association (AHA) and American Stroke Association (ASA) have updated their guideline on prevention of future stroke in patients with a history of stroke or transient ischemic attack (TIA). Currently, the average annual rate of future stroke in these patients is at a historic low.

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