ITEMS IN AFP WITH KEYWORD:
Stroke and TIA
Based on a recent randomized controlled trial followed by a systematic review, the BMJ and MAGIC group concluded that dual antiplatelet therapy use for a limited period after mild stroke is beneficial.
Combined treatment with clopidogrel and aspirin, started within 24 hours of the first event, will decrease the likelihood of a recurrent stroke in an additional 2% of patients compared with aspirin alone, with a slight increase in the risk of extra-cranial bleeding.
Aug 15, 2019 Issue
Asthma, Back and Neck Pain, Pain During Labor, TIA, CBT for Anxiety [AFP Clinical Answers]
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for the use of direct oral a...
This study provides support for a strategy of adding clopidogrel to aspirin for the first week or so after a minor ischemic stroke or TIA because this is when the greatest benefit occurs. Harms were spread fairly evenly throughout the study period.
Although the association between stroke and depression is well known and prevalent, it is often overlooked.
For nonhypoxic patients with acute stroke, routine oxygen therapy for 72 hours, either continuously or at night only, does not improve functional outcomes at 90 days. Long-term outcomes were not assessed in this study, and the question remains whether 90 days is an adequate length of time to see most of the meaningful recovery from stroke.
Prescription niacin (nicotinic acid, vitamin B3) does not reduce myocardial infarctions, strokes, or overall mortality when used for primary or secondary prevention.
Antiplatelet therapy, such as aspirin, clopidogrel, and aspirin/dipyridamole, is recommended to reduce the risk of recurrence after an initial stroke. Controlling risk factors and implementing lifestyle modifications, including smoking cessation, reducing alcohol intake, and increasing physical activity, are also important.
Jun 1, 2017 Issue
Physical Fitness Training for Patients with Stroke [Cochrane for Clinicians]
There is moderate-quality evidence that physical fitness training improves disability after stroke. Cardiovascular training that includes only aerobic exercise has a moderate effect on disability (standard mean difference [SMD] = 0.52 on a pooled disability scale), although it is not clear whether t...