ITEMS IN AFP WITH KEYWORD:
Stroke and TIA
In patients at high risk of stroke because of nonvalvular atrial fibrillation, rivaroxaban is as safe and effective as warfarin. However, it should not be used in patients at risk of stroke for reasons other than nonvalvular atrial fibrillation until research shows its relative safety and effectiveness.
Transient ischemic attack is defined as transient neurologic symptoms without evidence of acute infarction. It is a common and important risk factor for future stroke, but is greatly underreported. Common symptoms are sudden and transient, and include unilateral paresis, speech disturbance, and mono...
Interventions following a transient ischemic attack are aimed at preventing a future episode or stroke. Hypertension, current smoking, obesity, physical inactivity, diabetes mellitus, and dyslipidemia are all well-known risk factors, and controlling these factors can have dramatic effects on transie...
Dabigatran is superior to warfarin for stroke prevention in patients with atrial fibrillation, with similar rates of major bleeding. Because it does not require laboratory monitoring, dabigatran therapy is less complicated than warfarin therapy, but it costs significantly more.
Ischemic stroke is the third leading cause of death in the United States and a common reason for hospitalization. The subacute period after a stroke refers to the time when the decision to not employ thrombolytics is made up until two weeks after the stroke occurred. Family physicians are often invo...
Is CT sensitive enough to rule out subarachnoid hemorrhage? This study says yes, but rretrospective studies are inherently problematic. Normal head CT should be followed by a lumbar puncture.
Apr 15, 2011 Issue
AHA/ASA Guidelines on Prevention of Recurrent Stroke [Practice Guidelines]
Persons who survive a stroke or transient ischemic attack (TIA) are at increased risk of experiencing another stroke. The American Heart Association (AHA) and the American Stroke Association (ASA) have released updated guidelines on preventing recurrent stroke in patients who have had a previous stroke or TIA.
Computed tomography (CT) is the diagnostic standard for acute stroke even though its accuracy has not been formally established. Its sensitivity for diagnosing ischemic stroke in the initial hours is limited; therefore, improved accuracy is needed to develop and provide optimal stroke treatment. The...
Apr 1, 2010 Issue
Effectiveness of B-Complex Vitamins for Prevention of Cardiovascular Events [Cochrane for Clinicians]
Eight randomized clinical trials that included 24,210 patients did not show a reduction in MI, stroke, or all-cause mortality with B-complex vitamin therapy.
Does telmisartan therapy after stroke prevent recurrence and adverse cardiovascular events? Despite lowering blood pressure, telmisartan did not provide preventative benefit. This study reflects problems with publication bias and that surrogate markers, such as blood pressure control, may not reflect patient outcomes.