Substance Abuse

Feb 1, 2008 Issue
Adolescent Substance Use and Abuse: Recognition and Management [Article]

Screening for substance use is recommended for all adolescents. If screening is positive, physicians can conduct an in-depth evaluation or refer the patient to a subspecialist. Treatment involves multiple therapeutic components for the abuse and its comorbid disorders. Ongoing lethality assessment is essential.

Oct 15, 2007 Issue
Methamphetamine Abuse [Article]

Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamph...

May 1, 2006 Issue
Managing Opioid Addiction with Buprenorphine [Article]

Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for man...

Jun 1, 2004 Issue
Club Drugs: MDMA, Gamma-Hydroxybutyrate (GHB), Rohypnol, and Ketamine [Article]

Club drugs are substances commonly used at nightclubs, music festivals, raves, and dance parties to enhance social intimacy and sensory stimulation. The most widely used club drugs are 3,4-methylenedioxymethamphetamine (MDMA), also known as ecstasy; gamma-hydroxybutyrate (GHB); flunitrazepam (Rohypn...

May 15, 2004 Issue
Routine Screening for Depression, Alcohol Problems, and Domestic Violence [Point-of-Care Guides]

During routine office visits, primary care physicians are expected to efficiently and effectively screen their patients for common, important conditions. Routine screening for depression is recommended by the U.S. Preventive Services Task Force (USPSTF) as long as systems are in place to ensure accu...

Nov 15, 2003 Issue
Common Problems in Patients Recovering from Chemical Dependency [Article]

Chemical dependency is a common, chronic disease that affects up to 25 percent of patients seen in primary care practices. The treatment goal for patients recovering from chemical dependency should be to avoid relapse. This requires physicians to have an open, nonjudgmental attitude and specific exp...

Sep 1, 2003 Issue
Recognition and Prevention of Inhalant Abuse [Article]

Inhalant abuse is a prevalent and often overlooked form of substance abuse in adolescents. Survey results consistently show that nearly 20 percent of children in middle school and high school have experimented with inhaled substances. The method of delivery is inhalation of a solvent from its contai...

Jun 15, 2001 Issue
Methadone Therapy for Opioid Dependence [Article]

The 1999 Federal regulations extend the treatment options of methadone-maintained opioid-dependent patients from specialized clinics to office-based opioid therapy (OBOT). OBOT allows primary care physicians to coordinate methadone therapy in this group with ongoing medical care. This patient group ...

Dec 1, 2000 Issue
Gamma-Hydroxybutyrate (GHB): A Newer Drug of Abuse [Article]

Gamma-hydroxybutyrate (GHB) is an illicitly marketed substance that has recently gained popularity among body builders and party attendees as a drug of abuse. GHB is a depressant that acts on the central nervous system. It is purported as a strength enhancer, euphoriant and aphrodisiac and is one of...

May 1, 2000 Issue
An Approach to Drug Abuse, Intoxication and Withdrawal [Article]

The symptomatic effects of drug abuse are a result of alterations in the functioning of the following neurotransmitters or their receptors: acetylcholine, dopamine, gamma-aminobutyric acid, norepinephrine, opioids and serotonin. Anticholinergic drugs antagonize acetylcholine receptors. Dissociative ...

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