Upper Respiratory Infections

Oct 01, 2021 Issue
High-Dose Amoxicillin/Clavulanate No Better than Standard Dose for Acute Sinusitis in Adults [POEMs]

This study found no significant difference between the standard-dose and high-dose regimens of amoxicillin/clavulanate for treating acute sinusitis in adults. It is important to note that both doses are minimally superior to placebo.

Sep 01, 2021 Issue
Take-and-Hold Prescriptions for Children with Respiratory Tract Infections Decrease Antibiotic Use with Similar Outcomes [POEMs]

A strategy of providing education about the natural history of respiratory symptoms in children combined with giving a take-and-hold prescription (to be filled only if symptoms persisted) resulted in one in four of those children eventually receiving an antibiotic.

Mar 15, 2021 Issue
Helping Ambivalent Patients Make Healthy Decisions About COVID-19 [Lown Right Care: Reducing Overuse and Underuse]

A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

Feb 1, 2021 Issue
Exercise vs. No Exercise for the Occurrence, Severity, and Duration of Acute Respiratory Tract Infections [Cochrane for Clinicians]

For adults, regular exercise may reduce the overall severity of acute respiratory tract infections and the number of days with symptoms, but there is no evidence that exercise reduces the overall occurrence or duration of these infections.

Nov 1, 2020 Issue
Antibiotics for Acute Bronchitis [Medicine by the Numbers]

Acute bronchitis is a lower respiratory tract infection, most commonly viral, that accounts for a significant number of health care visits. This review discusses the benefits and harms of antibiotics for acute bronchitis or acute productive cough.

Sep 15, 2019 Issue
Normal Vital Signs and Pulmonary Examination Results Rule Out CAP in Adults with Acute Respiratory Infection [POEMs]

Community-dwelling adults who present to a primary care office with acute respiratory infection symptoms but normal vital signs and normal findings on a pulmonary examination have only a 0.4% likelihood of community-acquired pneumonia (CAP).

Sep 1, 2019 Issue
Treatment of the Common Cold [Article]

Find out how to distinguish the common cold from other conditions, get tips for managing patients’ expectations and preventing unnecessary antibiotic prescriptions, and get the latest evidence on which treatments are effective for children and adults.

Apr 1, 2019 Issue
Testicular Cancer, Onset of Labor, Respiratory Tract Infection, Thyroid Cancer, Running Injuries [AFP Clinical Answers]

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

Jul 1, 2018 Issue
Procalcitonin to Guide Antibiotic Therapy in Acute Respiratory Infections [Cochrane for Clinicians]

Procalcitonin-guided antibiotic therapy, when compared with routine treatments, results in decreased mortality in patients with acute respiratory infections (absolute risk reduction [ARR] = 1.4%; number needed to treat [NNT] = 71).

May 1, 2018 Issue
Croup: Diagnosis and Management [Article]

Croup is primarily a clinical diagnosis, with typical findings of abrupt onset of a barking cough, inspiratory stridor, and hoarseness in children six months to three years of age. Differentiating croup from other acute illnesses can be challenging. Find out which clinical signs and symptoms are most accurate for diagnosing croup, and which treatments have the strongest evidence.

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