Vascular Disorders

Feb 01, 2022 Issue
Hyperpigmented Reticular Patches in a Young Adult [Photo Quiz]

A patient presented with faint, dark purple, hyperpigmented patches in a reticular pattern, forming several complete rings, on his dorsal thighs and a few on his lower legs and arms.

Jan 01, 2022 Issue
Arterial Atherosclerosis: Vascular Surgery Interventions [Article]

Atherosclerotic vascular disease is a leading cause of death worldwide. Atherosclerotic stenosis of the internal carotid or intracranial arteries causes up to 15% of strokes. Peripheral artery disease affects up to one in five people in the United States who are 60 years and older and nearly one-hal...

May 15, 2020 Issue
Surgery or Lasers Preferred to Foam Sclerotherapy for Varicose Veins [POEMs]

For symptomatic varicose veins at least 3 mm in diameter with evidence of saphenous vein reflux, laser ablation is the preferred initial therapy.

May 1, 2020 Issue
Lower Extremity Petechiae and Purpura [Photo Quiz]

A patient presented with a nontender, symmetrical petechial and purpuric rash from the soles to the lower abdomen.

Feb 1, 2020 Issue
Painful Lower Extremity Ulcerations with Hyperpigmentation [Photo Quiz]

Jun 1, 2019 Issue
Varicose Veins: Diagnosis and Treatment [Article]

The pathophysiology of varicose veins involves a genetic predisposition, incompetent valves, weakened vascular walls, and increased intravenous pressure. Established risk factors include family history of venous disease, female sex, older age, chronically increased intra-abdominal pressure, deep venous thrombosis, and arteriovenous shunting. Current guidelines recommend endovenous thermal ablation as first-line therapy for nonpregnant patients, followed by endovenous sclerotherapy and surgery. Conservative measures are recommended for patients who are not candidates for endovenous or surgical management, do not desire intervention, or are pregnant.

Nov 1, 2018 Issue
Abrupt Rash with Painful, Nonpruritic Purpura on the Lower Extremities [Photo Quiz]

Oct 1, 2017 Issue
In Very High-Risk Patients with Vascular Disease, Evolocumab Slightly Reduces Nonfatal MI But Not Mortality [POEMs]

In an extremely high-risk group of patients with known vascular disease, taking evolocumab instead of placebo in addition to standard statin therapy for slightly more than two years will prevent one myocardial infarction (MI) for every 83 persons treated and prevent one stroke for every 250 persons treated.

May 15, 2017 Issue
Venous Leg Ulcers [Clinical Evidence Handbook]

What are the effects of treatments for venous leg ulcers? What are the effects of various interventions for venous leg ulcers?

Jan 15, 2017 Issue
Giant Cell Arteritis: Biopsy After Corticosteroid Initiation [FPIN's Clinical Inquiries]

Corticosteroid therapy in patients with suspected giant cell arteritis should not degrade the accuracy of temporal artery biopsy if the biopsy is performed within four weeks of corticosteroid initiation. Temporal artery biopsy can be performed up to four weeks after starting high-dose corticosteroid therapy.

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