Vascular Disorders

Sep 15, 2014 Issue
Primary Raynaud Phenomenon [Clinical Evidence Handbook]

What are the effects of drug treatments for primary Raynaud phenomenon?

Aug 1, 2014 Issue
Effectiveness of Calcium Channel Blockers for Raynaud Phenomenon [Cochrane for Clinicians]

CCBs are modestly effective at reducing the frequency of attacks of primary Raynaud phenomenon. There is no evidence that attack severity or physiologic measurements are reduced by CCBs. Treatment is associated with adverse effects such as headache, flushing, and edema.

Aug 1, 2014 Issue
Purpura and Cough [Photo Quiz]

A 21-year-old man presented with fever, cough, arthralgias, and bilateral lower extremity rash and swelling that began 24 hours earlier.

Jan 15, 2014 Issue
Anemia and Mucocutaneous Telangiectasias [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photgraph or other image.

Dec 15, 2013 Issue
Ticagrelor (Brilinta) for Secondary Prevention of Thrombotic Events Following Acute Coronary Syndrome [STEPS]

Ticagrelor is an alternative to clopidogrel for secondary prevention of cardiovascular death in patients with acute coronary syndrome. In an international study it was found to be more effective, but patients in the United States did not experience superior outcomes.

Dec 15, 2013 Issue
AHA Releases Recommendation on Ankle-Brachial Index Measurement and Interpretation [Practice Guidelines]

The ankle-brachial index (ABI) is the ratio of the systolic blood pressure at the ankle to the systolic blood pressure at the brachial artery. The American Heart Association (AHA) released a scientific statement on the measurement and interpretation of ABI, including standardization of measurement technique and the threshold for diagnosing PAD.

Jun 15, 2012 Issue
ACP Recommendations for VTE Prophylaxis in Hospitalized Patients [Practice Guidelines]

Most hospitalized patients have at least one risk factor for venous thromboembolism (VTE), such as pulmonary embolism or deep venous thrombosis. The American College of Physicians (ACP) has released guidelines on VTE prophylaxis in hospitalized, nonsurgical patients, including those with acute stroke.

Jun 15, 2012 Issue
Transient Ischemic Attack: The Rules Have Changed [AFP Journal Club]

This scientific guideline includes three game changers for physicians regarding TIA. The Journal Club authors discuss why physicians should be wary of clinical guidelines that are based on expert opinion.

May 15, 2012 Issue
ACCF/AHA Update Peripheral Artery Disease Management Guideline [Practice Guidelines]

The American College of Cardiology Foundation (ACCF) and American Heart Association (AHA) have updated their 2005 guideline on the management of peripheral artery disease (PAD) based on new data, with particular focus on lower extremity and abdominal aortic disease. Recommendations for renal and mesenteric disease remain the same.

Jun 15, 2011 Issue
Appropriate Aspirin Use for Primary Prevention of Cardiovascular Disease [Editorials: Controversies in Family Medicine]

The factor most strongly associated with appropriate aspirin use is a conversation between the patient and physician. The National Committee for Quality Assurance has proposed that health plans measure their members' use of aspirin, as well as the extent to which physicians discuss aspirin use with ...

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