Nov 15, 2017 Issue
Mite-Impermeable Covers Decrease Hospital Visits in Kids with Asthma [POEMs]

In children with house dust mite allergies and asthma, the use of mite-impermeable bedding decreases the frequency of asthma exacerbations.

Nov 15, 2017 Issue
Reslizumab (Cinqair) for Eosinophilic Asthma [STEPS]

Reslizumab is an expensive treatment option for decreasing exacerbations in patients with severe asthma and pronounced eosinophilia. Because of the risk of anaphylaxis, it should only be administered in an appropriate facility by a medical professional. Reslizumab is best considered after other treatments have proved ineffective.

Sep 1, 2017 Issue
Vitamin D for the Management of Asthma [Cochrane for Clinicians]

Despite the authors' caution that further data are needed to clarify the role of vitamin D in care, this Cochrane review found that its use reduces the average number of asthma exacerbations requiring corticosteroid treatment from 0.44 to 0.28 per person per year.

Aug 1, 2017 Issue
Effects of Yoga in Patients with Asthma [Cochrane for Clinicians]

Regular yoga improves quality of life as measured on the Asthma Quality of Life Questionnaire (mean difference = 0.57 units on a seven-point scale; 95% confidence interval [CI], 0.37 to 0.77); improves asthma symptoms (standardized mean difference = 0.37; 95% CI, 0.09 to 0.65); and reduces medicatio...

May 1, 2017 Issue
One-Third of Adults with Diagnosed Asthma Can Be Weaned Off All Asthma Medications [POEMs]

This study found that current asthma was ruled out after repeated testing in one-third of adults with physician-diagnosed asthma. Patients ruled out for current asthma were less likely to be using asthma medications or daily controlling medications and less likely to have undergone testing for airflow limitation at the time of initial diagnosis.

Mar 15, 2017 Issue
Single-Dose Dexamethasone an Option for Acute Adult Asthma [POEMs]

A single dose of 12-mg dexamethasone, which has a longer duration of action than prednisone, is almost as effective as five days of 60-mg prednisone for the prevention of relapse in adults with acute asthma treated in an emergency department.

Sep 15, 2016 Issue
Medications for Chronic Asthma [Article]

Therapeutic agents used in the management of chronic asthma aim to prevent symptoms by controlling airway inflammation and hyperreactivity. Medication regimens are organized in stepwise approaches based on patient age. Data regarding the safety and efficacy of popular complementary and alternative asthma treatments are largely unavailable.

Sep 1, 2016 Issue
Inhaled Fluticasone-Salmeterol Better Than Fluticasone Alone for Moderate to Severe Asthma [POEMs]

The combination of fluticasone and salmeterol (Advair), with the steroid dose adjusted for disease severity, reduces the number of severe asthma exacerbations more than fluticasone (Flovent) alone (number needed to treat [NNT] = 50 over 26 weeks), with no difference in terms of potential harms, such as intubation or asthma-related death.

Aug 15, 2016 Issue
Single-Dose Dexamethasone Equals Three Days of Steroids in Children with Acute Asthma [POEMs]

In addition to usual beta-agonist treatment, a single dose of oral dexamethasone is as effective as three days of prednisolone (with less vomiting) in decreasing respiratory symptoms without increasing hospitalizations, follow-up visits, and days lost from school. Additional treatment with a steroid...

Jul 1, 2016 Issue
Intermittent Inhaled Corticosteroid Therapy for Mild Persistent Asthma in Children and Adults [Cochrane for Clinicians]

Intermittent inhaled corticosteroid therapy reduces the risk of asthma exacerbations in children and adults with mild persistent asthma. Intermittent use appears to be safe in these patients.

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