Chronic kidney disease (CKD) is steadily increasing in prevalence in the United States, causing significant morbidity and mortality. There is reasonable evidence that specific actions can be implemented by primary care physicians to delay CKD progression and reduce mortality. The availability of computer decision support (CDS) for CKD may help promote effective, evidence-based care. This group randomized controlled trial will test the extent to which CDS, plus practice facilitation, promotes evidence-based care and improves the clinical outcomes of reduced disease progression and mortality in primary care practices. This study will enroll 40 practices associated with the Distributed Ambulatory Research in Therapeutics Network (DARTNet), a federated network of organizations that use electronic health records.
This project was funded from September 2011 through August 2016.
The project is in the data analysis phase.
Effect of 2 Clinical Decision Support Strategies on Chronic Kidney Disease Outcomes in Primary Care A Cluster Randomized Trial. Carroll JK, Pulver G, Dickinson LM, Pace WD, Vassalotti JA, Kimminau KS, Manning BK, Staton EW, Fox CH,JAMA Network Open. 2018;1(6):e183377.
Recruiting primary care practices for practice-based research: a case study of a group-randomized study (TRANSLATE CKD) recruitment process. Loskutova NY, Smail C, Ajayi K, Pace WD, Fox CH. Fam Pract. July 2017 (1- 6) cmx064. doi: 10.1093/fampra/cmx064
Chronic Kidney Disease Guideline Implementation in Primary Care: A Qualitative Study of Providers in the TRANSLATE CKD Study.Vest BM, York TRM, Sand J, Fox CH, Kahn LS. J Am Board Fam Med. September-October 2015; 28(5):624-31.
Pragmatic Cluster Randomized Trials Using Covariate Constrained Randomization: A Method for Practice-based Rsearch Networks (PBRNs). Dickinson LM, Beaty B, Fox CH, Pace WD, Dickinson WP, Emsermann C, Kempe A. J Am Board Fam Med. September-October 2015; 28(5):663-72.
Inaccuracy of ICD-9 Codes for Chronic Kidney Disease: A Study from Two Practice-based Research Networks (PBRNs). Cipparone CW, Withiam-Leith M, Kimminau KS, Fox CH, Singh R, Kahn L. J Am Board Fam Med. September-October 2015; 28(5):678-82.
Importance of urine albumin creatinine ratio in the diagnosis and prognosis of chronic kidney disease.Fox CH, Neuhaus K, Vassalotti JA. OA Nephrology 2013 Nov 01;1(3):21.
Improving evidence-based primary care for chronic kidney disease: study protocol for a cluster randomized control trial for translating evidence into practice (TRANSLATE CKD). Fox CH, Vest BM, et al. Implementation Sci. 2013;8:88.
For additional information about this study, please contact:
Brian Manning, MPH, CHES
Associate Research Director
AAFP National Research Network
1-800-274-2237, ext. 6151
This project was funded by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH.