The influenza vaccine recommendations change every year. In addition to communicating these updates, AAFP recommends offering annual flu shots to patients 6 months and older who don't have contraindications for the immunization.
In late August, ACIP released several primary updates for clinicians. Read more in New Influenza Vaccine Recommendations for 2021-2022 Season.
To protect your patients from related illness and health complications, promote the influenza vaccination as soon as it's available each year and provide the vaccine throughout the flu season (i.e., as long as influenza viruses are circulating in the community). Vaccination is especially important as the COVID-19 pandemic continues.
Last year, family physicians shared their perspectives in:
As flu season approaches, your patients may have questions about the difference between COVID-19 and the flu. Consider sharing:
For the 2021-2022 season, there is no preferential recommendation for any one flu vaccine over another.
Your recommendation to pregnant patients makes a difference in protecting expectant mothers and their infants from influenza-related illnesses, hospitalization, and premature labor and delivery. Consider the following points in discussions with expectant mothers:
The AAFP supports annual mandatory influenza immunization for health care personnel (HCP), except for refusal due to a documented allergy or medical contraindication. If HCP are not vaccinated, policies to adjust practice activities during flu season are appropriate (e.g., wearing masks, refraining from direct patient care). (AAFP Board of Directors, May 2016)
As is the case for all vaccines, influenza vaccines contain components that might cause allergic and anaphylactic reactions.Not all such reactions are related to egg proteins; however, the possibility of reactions to influenza vaccines in patients who are egg allergic might be of concern to these patients and vaccine providers.
Currently available influenza vaccines, with the exceptions of recombinant influenza vaccine (RIV4;FluBlok Quadrivalent, licensed for ages 18 and older) and cell-culture-based inactivated influenza vaccine (ccIIV4;Flucelvax Quadrivalent, licensed for ages 4 and older), are prepared by propagation of virus in embryonated eggs and might contain trace amounts of egg proteins, such as ovalbumin.
Severe allergic reactions to vaccines, although rare, can occur at any time, even in the absence of a history of previous allergic reaction. Therefore, all vaccine providers should be familiar with the office emergency plan and be certified in cardiopulmonary resuscitation. For patients who report a history of egg allergy, the CDC's Advisory Committee on Immunization Practices (ACIP) recommends patients with a history of egg allergy who have experienced only urticaria after exposure to egg should receive influenza vaccine. Any licensed, recommended influenza vaccine (i.e., any IIV, RIV4, or LAIV4) that is otherwise appropriate for the recipient's age and health status may be used.
Patients who report having had reactions to egg involving symptoms other than urticaria (e.g., angioedema or swelling, respiratory distress, lightheadedness, or recurrent vomiting) or who required epinephrine or another emergency medical intervention may similarly receive any licensed, recommended influenza vaccine (i.e., any IIV, RIV4, or LAIV4) that is otherwise appropriate for their age and health status. The selected vaccine should be administered in an inpatient or outpatient medical setting (including, but not necessarily limited to, hospitals, clinics, health departments, and physician offices). Vaccine administration should be supervised by a health care professional who is able to recognize and manage severe allergic reactions.
A previous severe allergic reaction to influenza vaccine, regardless of the component suspected of being responsible for the reaction, is a contraindication to future receipt of the vaccine.
No postvaccination observation period is recommended specifically for patients who are egg allergic. However, the ACIP recommends that vaccine providers consider observing patients (seated or supine) for 15 minutes after administration of any vaccine to decrease the risk for injury should syncope occur.
Patients who are able to eat lightly cooked eggs (e.g., scrambled eggs) without a reaction are unlikely to be allergic. Patients who are egg-allergic might tolerate egg in baked products (e.g., bread or cake). However, tolerance to egg-containing foods does not exclude the possibility of egg allergy. Egg allergy can be confirmed by a consistent medical history of adverse reactions to eggs and egg-containing foods, plus skin or blood testing for immunoglobulin E directed against egg proteins.
Occasional cases of anaphylaxis after administration of influenza vaccines in patients who are have been reported to the Vaccine Adverse Event Reporting System (VAERS). The ACIP will continue to review available data regarding anaphylaxis cases after receipt of influenza vaccines.