• Rationale and Comments

    Measurements of the level of vitamin K in the blood are rarely used to determine if a deficiency exists. Vitamin K deficiency is very rare, but when it does occur, a prolonged prothrombin time and elevated international normalized ratio will result. A diagnosis is typically made by observing the prothrombin time correction following administration of vitamin K, plus the presence of clinical risk factors for vitamin K deficiency.

    Sponsoring Organizations

    • American Society for Clinical Pathology


    • Expert consensus


    • Hematologic


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