Health care professionals should not perform cervical cancer screening in women who have had a hysterectomy that removed their cervix and do not have a history of high-grade precancerous lesions or cervical cancer. Screening provides no benefits to these patients and may subject them to potential risks from false-positive results, including physical (e.g., vaginal bleeding from biopsies) or psychological (e.g., anxiety). In addition, cervical cancer screening should not be performed in women over the age of 65 that are at low risk for cervical cancer and have had negative results from prior screenings. Health care professionals should make this decision on a case-by-case basis, but once a patient stops receiving screenings, in general, they should not restart screenings. Screening for women in this population provides little to no benefit because the incidence and prevalence of cervical disease declines for women starting at age 40–50 years.