Rationale and Comments

Mild dysplasia (cervical intraepithelial neoplasia 1) is associated with the presence of human papillomavirus (HPV), which does not require treatment in average-risk women. Most women with cervical intraepithelial neoplasia 1 on biopsy have a transient HPV infection that will usually clear in less than 12 months and, therefore, does not require treatment.

Sponsoring Organizations

• American College of Obstetricians and Gynecologists

Sources

• American Society for Colposcopy and Cervical Pathology guidelines
• American College of Obstetricians and Gynecologists guidelines

Disciplines

• Gynecologic
• Oncologic

References

• Wright TC, et al. 2006 consensus guidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ. Am J Obstet Gynecol. 2007;197:340-5.
  
• American College of Obstetricians and Gynecologists. Management of abnormal cervical cytology and histology. Practice bulletin no. 99. Obstet Gynecol. 2008;112:1419-44.