• Rationale and Comments

    Antiepileptic drug level testing should not be routinely ordered when seizures are well controlled, and no adverse effect is suspected. The reference ranges should not be used as a rigid framework. The effectiveness and tolerability of treatments should be determined by the clinical responses. Antiepileptic drug levels should be ordered to address a specific question. Some examples include weight-based dosing adjustments in young children, adherence, suspected toxicity, and pregnant women.

    Sponsoring Organizations

    • American Epilepsy Society


    • Cochrane Database of Systematic Reviews


    • Neurologic


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