• Rationale and Comments

    Most cases of maxillary sinusitis in the ambulatory setting are caused by a viral infection that will resolve on its own. Despite consistent recommendations to the contrary, antibiotics are prescribed in more than 80% of outpatient visits for acute sinusitis. Sinusitis accounts for 16 million office visits and $5.8 billion in annual health care costs.

    Sponsoring Organizations

    • American Academy of Allergy, Asthma and Immunology
    • American Academy of Family Physicians
    • American Academy of Otolaryngology–Head and Neck Surgery Foundation


    • Cochrane Database of Systematic Reviews
    • Annals of Internal Medicine


    • Infectious disease
    • Otolaryngologic


    • Centers for Disease Control and Prevention
    • Annals of Internal Medicine
    • Ahovuo-Saloranta A, et al. Antibiotics for acute maxillary sinusitis. Cochrane Database Syst Rev. 2008;(2):CD000243.