• Rationale and Comments

    There is adequate evidence that the harms of HPV testing, alone or in combination with cytology, in women younger than 30 years are moderate. The harms include more frequent testing and invasive diagnostic procedures such as colposcopy and cervical biopsy. Abnormal screening test results are also associated with psychological harms, anxiety, and distress.

    Sponsoring Organizations

    • American Academy of Family Physicians


    • U.S. Preventive Services Task Force


    • Gynecologic
    • Oncologic
    • Preventive Medicine


    • American Academy of Family Physicians. Screening for cervical cancer policy. http://www.aafp.org/online/en/home/clinical/ exam/cervicalcancer.html.
    • U.S. Preventive Services Task Force. Screening for cervical cancer. http://www.uspreventiveservicestaskforce.org/uspstf/ uspscerv.htm.
    • Vesco KK, et al. Screening for cervical cancer: a systematic evidence review for the U.S. Preventive Services Task Force. Rockville, Md.: Agency for Healthcare Research and Quality; 2011. http://preview.ncbi.nlm.nih.gov/bookshelf/booktest/ br.fcgi?book=es86.