Health care workers
Rubber industry workers
Persons witih spina bifida or urogenital abnormalities
Persons who have undergone repeated or prolonged surgeries or mucous membrane exposure to latex devices, especially early in life
Persons with an atopic history or history of food allergy (cross-reacting proteins, especially in banana, avocado, passion fruit, chestnut, kiwi fruit, melon, tomato, celery)