Threat to life or function
Kasabach-Merritt syndrome (coagulopathy)
Anatomic site
Vision impairment
Respiratory impairment
High-output cardiac failure (mortality up to 50 percent)11
Hepatic lesions
Other internal lesions
Location in scarprone area
Nose
Lip
Ear
Glabellar area
Any large facial hemangiomas
Pedunculated lesions
Tendency to bleed or to become infected
Rapid rate of growth (tripling in size within weeks)