| Contraindications |
| Uncompensated congestive heart failure |
| Pulmonary hypertension |
| Sickle cell anemia |
| Severe COPD |
| Cautions |
| Compensated congestive heart failure |
| Troublesome arrhythmias |
| Sickle cell trait |
| Moderate COPD |
| Seizure disorders (not controlled on medication) |
| Stable angina or coronary artery disease |
| Sleep apnea |
| High-risk pregnancy |