Preferred initial regimen
Two nucleoside analogs + a highly active protease inhibitor, such as ritonavir (Norvir), indinavir (Crixivan), nelfinavir (Viracept) or saquinavir (Fortovase)
Alternative initial regimens
Two nucleoside analogs + a nonnucleoside reverse transcriptase inhibitor
Two nucleoside analogs + saquinavir
Two nucleoside analogs (although not generally recommended)
Regimens not recommended
Monotherapy
Stavudine (Zerit) + zidovudine (Retrovir)
Zalcitabine (Hivid) + didanosine (Videx)
Zalcitabine + stavudine
Zalcitabine + lamivudine (Epivir)
Suggested regimens for patients who fail to respond to initial therapy
• If initial regimen was two nucleoside analogs and a protease inhibitor, change to one of the following:
	Two different nucleoside analogs + a different protease inhibitor
	Two different nucleoside analogs + a protease inhibitor combination
	Two different nucleoside analogs + a protease inhibitor + a nonnucleoside reverse transcriptase inhibitor
• If initial regimen was two nucleoside analogs and a nonnucleoside reverse transcriptase inhibitor, change to the following:
	Two different nucleoside analogs + a protease inhibitor
• If initial regimen was two nucleoside analogs, change to the following:
	Two different nucleoside analogs + a protease inhibitor
• If initial regimen was one nucleoside analog, change to one of the following:
	Two different nucleoside analogs + a protease inhibitor
	Two different nucleoside analogs + a nonnucleoside reverse transcriptase inhibitor