LesionLocationSurfaceColorOutlineOther features
Squamous cell carcinomaAreas exposed to sunlight, radiation or arsenicalsRough, irregular, sometimes scaly, sometimes has visible vessels, sometimes warty or with fleshy massesSkin-colored at first, sometimes reddened laterVagueNew lesions may appear near old ones
Does not clear with corticosteroid therapy
Keratoacanthoma (a variant of squamous cell carcinoma)Exposed areas, especially face and handsSmooth dome, becoming volcano-shapedSkin-colored or slightly reddenedWell-definedGoes through aperiod of very rapid growth, often regresses
Eczema and atopic dermatitis (Figure 13)Atopic dermatitis behind ears, on flexure areasReddened, slightly scaly, sometimes with vesiclesDry at first, fissured, may weepIndefiniteCommon in atopic persons and those exposed to irritants
Contact dermatitis (Figure 14)Wherever skin comes in contact with an irritantReddened, slightly scaly, sometimes with vesiclesDry at first, fissured, may weepCircumscribedDermatitis clears with corticosteroid therapy
Psoriasis (Figure 15)Elbows, knees, scalp, sacral cleft, nailsScaly with underlying reddened baseWhite dry scales, smooth pink or red wherescales are removed; may bleedWell-demarcated; round, irregular or confluentOften widespread, sometimes itchy; varies with season
Seborrheic dermatitis (Figure 16)Scalp, forehead, nasolabial fold, midline trunkRaised, with scalesYellow or brownWell-demarcatedSome lesions can be easily removed