Drug	Advantages	Disadvantages	Comment	Cost*
Corticosteroids	Easy to use, rapid onset	Tachyphylaxis, atrophy, telangiectasia and adrenal suppression possible	Can be used in combination with calcipotriene (Dovonex) or tazarotene (Tazorac)	†
Calcipotriene	Well-tolerated	Expensive, may cause skin irritation	Potential for hypercalcemia with excessive use	$78.00 per 60 g
Anthralin (Anthra-Derm)	Once-daily administration, well-tolerated	May stain and/or cause skin irritation	Microencapsulated form may be less staining and irritating	25.00 to 30.00
Tars	Effective with UV light therapy	May cause skin staining, folliculitis, contact allergy; malodorous	Commonly used for psoriasis of the scalp	†
Tazarotene		Expensive, may be teratogenic; irritating to uninvolved skin	First topical retinoid indicated by the FDA for treatment of psoriasis	60.00 to 212.00†