Diagnostic groupRoute of administrationDuration of therapyEmpiric optionsCost (generic)*
Acute uncomplicated urinary tract infections in womenOralThree daysTrimethoprim-sulfamethoxazole (Bactrim DS), one double-strength tablet twice daily$ 7.50 (2.00)
Trimethoprim (Proloprim), 100 mg twice daily4.00 (1.00)
Norfloxacin (Noroxin), 400 mg twice daily18.50
Ciprofloxacin (Cipro), 250 mg twice daily19.50
Lomefloxacin (Maxaquin), 400 mg per day20.00
Ofloxacin (Floxin), 200 mg twice daily21.00
Enoxacin (Penetrex), 200 mg twice daily18.00
Sparfloxacin (Zagam), 400 mg as initial dose, then 200 mg per day25.00
Levofloxacin (Levaquin), 250 mg per day19.00
Nitrofurantoin (Macrodantin), 100 mg four times daily17.00 (14.00)
Cefpodoxime (Vantin), 100 mg twice daily17.00
Cefixime (Suprax), 400 mg per day21.00
Amoxicillin-clavulanate potassium (Augmentin), 500 mg twice daily17.50
Acute uncomplicated pyelonephritisOral14 daysTrimethoprim-sulfamethoxazole DS, one double-strength tablet twice daily36.00 (11.00)
105.50
Ciprofloxacin, 500 mg twice daily
Levofloxacin, 250 mg per day92.00
Enoxacin, 400 mg twice daily191.00
Sparfloxacin, 400 mg initial dose, then 200 mg per day104.50
Ofloxacin, 400 mg twice daily124.50
Cefpodoxime, 200 mg twice daily111.00
Cefixime, 400 mg per day97.50
ParenteralUp to 3 daysTrimethoprim-sulfamethoxazole 160/800 twice daily32.00 (12.00) per day
Ceftriaxone (Rocephin), 1 g per day41.00 per day
Ciprofloxacin, 400 mg twice daily57.50 per day
Ofloxacin, 400 mg twice daily53.00 per day
Levofloxacin, 250 mg21.00 per day
Aztreonam (Azactam), 1 g three times daily48.50 per day
Gentamicin (Garamycin), 3 mg per kg per day in3 divided doses every 8 hours§12.50 (2.50 to3.00) per day
Complicated urinary tract infectionsOral14 daysFluoroquinolones
ParenteralUp to 3 daysAmpicillin, 1 g every six hours, and gentamicin, 3 mg per kg per day14.50 (5.00 to5.50) per day
Urinary tract infections in young menOralSeven daysTrimethoprim-sulfamethoxazole, one double-strength tablet twice daily18.00 (5.50)
Fluoroquinolones
Urinary tract infections in pregnant womenOralThree to seven daysAmoxicillin, 250 mg three times daily2.00 to 4.50(1.00 to 5.00)
Asymptomatic bacteriuria in pregnant womenOralThree to seven daysNitrofurantoin, 100 mg four times daily12.00 to 28.00(14.00 to 32.50)