| Properties and side effects | Bromocriptine (Parlodel) | Pergolide (Permax) | Pramipexole (Mirapex) | Ropinirole (Requip) | |
|---|---|---|---|---|---|
| Properties | |||||
| Initial dosage | 1.25 mg twice daily | 0.05 mg at bedtime | 0.125 mg three times daily | 0.25 mg three times daily | |
| Half-life | 10 to 12 hours | 16 to 24 hours | 8 hours | 6 hours | |
| Side effects | |||||
| Somnolence | + | ++ | +++ | ++ | |
| Insomnia | + | ++ | ++++ | + | |
| Dizziness or lightheadedness | +++ | +++ | +++ | ++ | |
| Hallucinations or confusion | +++ | ++ | ++ | ++ | |
| Headache | +++ | +++ | ++ | ||
| Orthostasis | +++ | +++ | ++ | +++ | |
| Nausea | ++++ | ++++ | ++++ | ++ | |
| Constipation | ++ | ++ | |||
| Others | |||||
| Arthralgia | ++ | ||||
| Blurred vision | ++ | + | |||
| Dry mouth | +++ | ++ | |||
| Pleurisy | ++ | ||||
| Upper respiratory Infection | ++ | ||||