Parameter affected	Estrogens	Raloxifene (Evista)	Alendronate (Fosamax)	Calcitonin (Calcimar, Miacalcin)
Bone mineral density	+	+	+	+
Lipids	+	+/0	0	0
Vasomotor symptoms	+	0	0	0
Endometrial proliferation	−	0	0	0
Breast cancer risk	−/0	?	0	0