| Mild to moderate PCP (oral regimens) | ||
| First choice | Trimethoprim-sulfamethoxazole (Bactrim, Septra) | |
| Second choice | Trimethoprim (Proloprim) and dapsone | |
| or | ||
| Clindamycin (Cleocin) and primaquine | ||
| Third choice | Atovaquone (Mepron) | |
| Moderate to severe PCP (IV regimens) | ||
| First choice | Trimethoprim-sulfamethoxazole | |
| Second choice | Trimetrexate/leucovorin and oral dapsone | |
| or | ||
| Clindamycin (Cleocin phosphate) and oral primaquine | ||
| Third choice | Pentamidine | |