Diagnostic category		Approximate prevalence*
“Functional” dyspepsia†		Up to 60 percent
Dyspepsia caused by structural or biochemical disease
	Peptic ulcer disease	15 to 25 percent
	Reflux esophagitis	5 to 15 percent
	Gastric or esophageal cancer	< 2 percent
	Biliary tract disease	Rare
	Gastroparesis	Rare
	Pancreatitis	Rare
	Carbohydrate malabsorption (lactose, sorbitol, fructose, mannitol)	Rare
	Medications (see Table 4)	Rare
	Infiltrative diseases of the stomach (Crohn's disease, sarcoidosis)	Rare
	Metabolic disturbances (hypercalcemia, hyperkalemia)	Rare
	Hepatoma	Rare
	Ischemic bowel disease	Rare
	Systemic disorders (diabetes mellitus, thyroid and parathyroid disorders, connective tissue disease)	Rare
	Intestinal parasites (Giardia, Strongyloides)	Rare
	Abdominal cancer, especially pancreatic cancer	Rare