DrugDosage*Comments
Unfractionated heparin5,000-U bolus (or 80 U per kg) IV, 1,300 U (or 18 U per kg) per hour IVMonitor activated partial thromboplastin time; in heparin resistance, target anti-Xa level of 0.4 to 0.7 U per mL
Low-molecular-weight heparin
Enoxaparin (Lovenox)1 mg per kg SC every 12 hoursFor all: when monitoring is required, target anti-Xa level of 0.4 to 0.7 U per mL
Dalteparin (Fragmin)100 anti-Xa U per kg SC every 12 hours
Ardeparin (Normiflo)?
Heparinoid
Danaparoid (Orgaran)2,500-U bolus IV; then 400 U per hour IV for 4 hours; then 300 U per hour IV for 4 hours; then 200 U per hour IVUse for heparin-induced thrombocytopenia; target anti-Xa level of 0.5 to 0.8 U per mL
When giving SC, 20 U per kg every 12 hours