Diagnosis	Frequency	Abnormal findings	Therapy
Hirschsprung's disease	1/4,0003	Tight anus, empty rectum, transition zone	Surgery
Meconium plug syndrome	1/500 to 1/1,00010	Meconium plugs	Rectal stimulation, enema
Meconium ileus	1/2,80012	Abdominal distention at birth, cystic fibrosis	Enema with intravenous fluids, surgery
Anorectal malformation	1/4,000 to 1/8,00014	Absent anus, tight anus or fistula	Dilatation, surgery
Small left colon syndrome	Rare	Transition zone* at splenic flexure	Enema, rarely, colostomy
Hypoganglionosis	Rare	Transition zone*	Medical, TPN, surgery
Neuronal intestinal dysplasia type A	Rare	Transition zone,* mucosal Inflammation	Medical, surgery
Neuronal intestinal dysplasia type B	Rare	Megacolon	Medical, rarely, surgery
Megacystis-microcolon-intestinal hypoperistalsis syndrome	Very rare	Microcolon, megacystis	TPN