Psychologic causes
Young age with abrupt onset
Onset associated with specific emotional event
Dysfunction in certain settings while normal function in others
Persistence of nocturnal erections
Previous history of erectile dysfunction with spontaneous improvement
Excessive life stressors—work, relationships
Mental status findings suggestive of depression, psychosis or anxiety disorder
Organic causes
Vasculogenic—arterial
Persistent interest in sex
Older age with gradual onset
Impaired function in all settings
Presence of chronic disease (particularly diabetes, hypertension)
Use of prescription/over-the-counter medications associated with erectile dysfunction
Smoking
Elevated blood pressure, evidence of peripheral vascular disease (bruits, decreased pulses, skin and hair changes consistent with arterial insufficiency)
Vasculogenic—venous
Inability to maintain erection once established
Prior history of priapism
Local anomalies of the penis
Neurogenic
History of spinal cord/pelvic trauma or surgery
Presence of chronic disease (diabetes, alcoholism)
Presence of neurologic condition (multiple sclerosis, stroke)
Abnormal neurologic examination of genitals/perineum
Hormonal
Loss of interest in sexual activity
Small atrophic testis
Low testosterone, elevated prolactin