Side effectsTreatment
NauseaMetoclopramide (Reglan), in a dosage of 5 to 10 mg four times daily, or a phenothiazine (e.g., promethazine [Phenergen]) is usually better tolerated than an antihistamine.
ConstipationFirst-line therapy is increased hydration and bulk agents.
Second-line treatment is lactulose (Cephulac) or a mild stimulant such as senna (e.g., Senokot) or bisacodyl (Dulcolax).
The last option is to use castor oil or products that contain magnesium.
SedationDextroamphetamine (Dexedrine), in a dosage of 2.5 to 5 mg twice daily, or methylphenidate (Ritalin), in a dosage of 2.5 to 5 mg twice daily
MyoclonusClonazepam (Klonopin), in a dosage of 0.5 mg three times daily, or nifedipine (Procardia), ina dosage of 10 mg three times daily
Respiratory depressionAs long as patient is oxygenating, a temporary reduction in narcotic dosage should suffice; rarely, a diluted, slowly administered dose of naloxone (Narcan) can be used.