Drugs	Comments
Analgesics
Indomethacin (Indocin)	More central nervous system side effects than any other nonsteroidal anti-inflammatory drug
Propoxyphene (Darvon)	Few advantages over acetaminophen and has narcotic side effects
Antihypertensives
Beta blockers	Can cause problems in patients with asthma or chronic obstructive pulmonary disease; may precipitate syncope because of negative inotropic and chronotropic effects
Reserpine*	Can cause depression, sedation and orthostatic hypotension
Miscellaneous
Antihistamines†	Highly anticholinergic
Cyclandelate (Cyclospasmol)	Generally ineffective for dementia or any other condition
Dipyridamole (Persantine)	Frequently causes orthostatic hypotension; of benefit only in patients with artificial heart valves
Ergoloid mesylates (Hydergine)	Generally ineffective for dementia or any other condition
Muscle relaxants	Increased cholinergic activity, sedation and weakness
Trimethobenzamide (Tigan)	Least effective antiemetic and can cause extrapyramidal symptoms