Symptoms

Anorexia

Fatigue

Mental status changes

Nausea and vomiting

Pruritus

Seizures (if blood urea nitrogen level is very high)

Shortness of breath (if volume overload is present)

Physical findings

Asterixis and myoclonus

Pericardial or pleural rub

Peripheral edema (if volume overload is present)

Pulmonary rales (if volume overload is present)

Elevated right atrial pressure (if volume overload is present)