Agent		Daily dosage (mg)	Duration of therapy (weeks)	Mean weight loss, kg (lb)
Agent		Daily dosage (mg)	Duration of therapy (weeks)	Treatment group	Placebo group
Phenylpropanolamine (Dexatrim)^12,13		20	14	6.1 (13.4)	4.3 (9.5)
Phenylpropanolamine (Dexatrim)^12,13		75	14	5.96 (13.1)	2.35 (5.2)
Phentermine (Ionamin)¹⁴		30.0 to 37.5	24	10.2 (22.4)	4.4 (9.7)
Fluoxetine (Prozac)*^15,16		60	12	6.0 (13.2)	6.7 (14.7)
Fluoxetine (Prozac)*^15,16		60	52	1.7 (3.7)	2.1 (4.6)
Sibutramine (Meridia)^17,18		10, 15	24	5.8, 6.4 (12.8, 14.1)	0.8 (1.8)
Sibutramine (Meridia)^17,18		15 to 30	96	2.6 (5.7)	-
Orlistat (Xenical)^19,20		120 three times daily	52	9.5 (20.9)	6.0 (13.2)