Type of obstructionCause and incidenceAge of onset and presentationsDiagnostic procedure and findingsPreoperative management interval before surgeryTreatmentPostoperative managementPrognosis
Duodenal atresiaEmbryogenic; occurs in 1 per 5,000 live births; 25% have Down syndromeFew hours after birth; bilious vomiting, no distentionAbdominal film, “double-bubble” signNasogastric suction, IV fluids; 24 to 48 hoursDiamond-shaped duodenoduodenostomyNo oral intake, nasogastric suction; feeding at 2 to 3 days after surgeryGood unless associated with serious anomalies
Malrotation with volvulusIncomplete bowel rotation occurring during 7th to 12th weeks of gestationAt 3 to 7 days; bilious vomiting, rapid deterioration with volvulusUpper GI spiral sign on ultrasound; abnormal location of the superior mesenteric vesselsNasogastric suction, IV fluid; STAT surgery for symptomatic patients, within daysfor othersLadd's procedure; may require a second laparotomyNo oral intake; nasogastric suctionGood without bowel resection, difficult with short-gut syndrome after bowel resection
Jejunoileal atresiaMesenteric vascular accident during fetal life in 1 per 3,000 live birthsWithin 24 hours of birth; vomiting, abdominal distentionAir-fluid levels on abdominal filmNasogastric suction, IV fluids; 12 to 24 hoursResection(s) and anastomosis(es)No oral intake, nasogastric suction; feeding at 2 to 4 days after surgeryGood unless excessive loss of bowel
Meconium ileusGenetic, occurs in 15% of newborns with cystic fibrosis, and in 1 per 5,000 to 10,000 live birthsImmediately after birth; abdominal distention, bilious vomitingAbdominal film; distention, air-fluid levels, sweat test, “ground-glass” signDecompressionEnterostomy if complicated; Gastrografin enema plus IV fluidsAcetylcysteine (Mucomyst), pancreatic enzymesDepends on the systemic problems
Necrotizing ileusCause unknown in 2.4 per 1,000 live births10 to 12 days after birth; distention, vomiting, bloody stoolsAbdominal film; distention, pneumatosis, air in the aortal veinNasogastric suction, IV fluids, nutrition, antibiotics for 10 days. When perforated, immediate surgeryResection of necrotic bowel and enterostomySame as preoperative management25% need surgery (65% survival rate) 75% can be treated medically (95% survival rate)