| Duodenal atresia | Embryogenic; occurs in 1 per 5,000 live births; 25% have Down syndrome | Few hours after birth; bilious vomiting, no distention | Abdominal film, “double-bubble” sign | Nasogastric suction, IV fluids; 24 to 48 hours | Diamond-shaped duodenoduodenostomy | No oral intake, nasogastric suction; feeding at 2 to 3 days after surgery | Good unless associated with serious anomalies |
| Malrotation with volvulus | Incomplete bowel rotation occurring during 7th to 12th weeks of gestation | At 3 to 7 days; bilious vomiting, rapid deterioration with volvulus | Upper GI spiral sign on ultrasound; abnormal location of the superior mesenteric vessels | Nasogastric suction, IV fluid; STAT surgery for symptomatic patients, within daysfor others | Ladd's procedure; may require a second laparotomy | No oral intake; nasogastric suction | Good without bowel resection, difficult with short-gut syndrome after bowel resection |
| Jejunoileal atresia | Mesenteric vascular accident during fetal life in 1 per 3,000 live births | Within 24 hours of birth; vomiting, abdominal distention | Air-fluid levels on abdominal film | Nasogastric suction, IV fluids; 12 to 24 hours | Resection(s) and anastomosis(es) | No oral intake, nasogastric suction; feeding at 2 to 4 days after surgery | Good unless excessive loss of bowel |
| Meconium ileus | Genetic, occurs in 15% of newborns with cystic fibrosis, and in 1 per 5,000 to 10,000 live births | Immediately after birth; abdominal distention, bilious vomiting | Abdominal film; distention, air-fluid levels, sweat test, “ground-glass” sign | Decompression | Enterostomy if complicated; Gastrografin enema plus IV fluids | Acetylcysteine (Mucomyst), pancreatic enzymes | Depends on the systemic problems |
| Necrotizing ileus | Cause unknown in 2.4 per 1,000 live births | 10 to 12 days after birth; distention, vomiting, bloody stools | Abdominal film; distention, pneumatosis, air in the aortal vein | Nasogastric suction, IV fluids, nutrition, antibiotics for 10 days. When perforated, immediate surgery | Resection of necrotic bowel and enterostomy | Same as preoperative management | 25% need surgery (65% survival rate) 75% can be treated medically (95% survival rate) |