Does the patient report “creeping, crawling or uncomfortable, difficult-to-describe feelings” in the legs or arms that are relieved by moving or rubbing them?

Is there a correlation between RLS symptoms and time of day? Do the symptoms worsen with rest or inactivity?

Do sensations interfere with sleep onset or returning to sleep?

What daytime consequences does the patient report (e.g., fatigue, sleepiness, confusion, lack of attention)?

Does the bed partner report that the patient's legs or arms jerk during sleep? (Relates to periodic limb movements of sleep.)

Does the patient have secondary causes of RLS, such as low iron stores, diabetes mellitus, kidney disease or pregnancy?

Are neurologic symptoms or diagnoses present?

Is there a relationship between symptoms and medications, such as tricyclic antidepressants or selective serotonin reuptake inhibitors?

Was the onset of symptoms correlated with a change in medication?

Do family members report similar symptoms? Have any family members been diagnosed with RLS?