Sudden weight gain

Central obesity

Hypertension

Facial plethora

Proximal muscle weakness

Glucose intolerance or diabetes mellitus

Decreased libido or impotence

Depression or psychosis

Osteopenia or osteoporosis

Easy bruising

Hyperlipidemia

Menstrual disorders

Violaceous striae wider than 1 cm

Recurrent opportunistic or bacterial infections

Acne

Hirsutism