Age >50 years	Temperature <35°C (95°F) or ≥40°C (104°F)
Pa O2 <60 mm Hg	WBC elevation >13,000 per mm3 (13 × 109 per L)
O2 saturation <90 percent	WBC suppression <4,000 per mm3 (4 × 109 per L)
Altered mental status	Hematocrit <30 percent (0.3)
Nursing home resident	BUN ≥30 mg per dL (11 mmol per L)
Comorbid illness*	Glucose ≥250 mg per dL (13.9 mmol per L)
Tachycardia ≥125 beats per minute	Sodium <130 mEq per L (130 mmol per L)
Tachypnea ≥30 breaths per minute	Radiographic evidence of progressing or multilobar infiltrates
Hypotension <90 mm Hg systolic	Pleural effusion