| Strong family history of diabetes |
| History of gestational diabetes |
| Polycystic ovary syndrome |
| Impaired glucose metabolism: fasting glucose level between 110 and 125 mg per dL (6.1 and 7.1 mmol per L) or impaired glucose tolerance, with a two-hour post–75-g glucose load level between 140 and 199 mg per dL (7.8 and 11.1 mmol per L)3 |
| Obesity: body mass index of 30 kg per m2 or more |
| Increased waist-to-hip ratio: 1.0 in men and 0.8 in women |