brand logo

Am Fam Physician. 2001;63(7):1296

The article “Use of Systemic Agents in the Treatment of Acne Vulgaris” (October 15, 2000, page 1823) contained an error in the dosage information for isotretinoin.

In two sentences on page 1828, the word “daily” should have been omitted. Those sentences should read as follows: (1) first column, ending sentence—“The average duration of therapy is five months, at which time most patients will have reached the desired goal of 120 to 150 mg per kg;” and (2) second column, second full paragraph, third sentence—“After reaching the goal dosage of 120 to 150 mg per kg, isotretinoin therapy should be discontinued even if the acne is not completely clear, because improvement continues for one to two months following cessation of treatment.” The total cumulative dosage of isotretinoin should be 120 to 150 mg per kg. This level is generally reached over five to six months when using a daily dosage of 0.5 to 1.0 mg per kg. In practice, the desired total dosage should be calculated for each patient. Then, using the actual prescribed daily dose, the duration of therapy may be customized, if necessary.

Continue Reading

More in AFP

Copyright © 2001 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.  See permissions for copyright questions and/or permission requests.