Vaccination statusTreatmentRegimen*
Not previously vaccinatedRIGAdminister 20 IU per kg body weight. If anatomically feasible, the fulldose should be infiltrated around the wound(s) and any remaining volume should be administered IM at an anatomic site distant from vaccine administration. Also, RIG should not be administered in the same syringe as vaccine. Because RIG may partially suppress active production of antibody, no more than the recommended dose should be given.
VaccineHDCV, RVA, or PCEC 1 mL, IM (deltoid area†), once daily on days 0‡, 3, 7, 14 and 28
Previously vaccinated§RIGRIG should not be administered.
VaccineHDCV, RVA, or PCEC 1.0 mL, IM (deltoid area†), once daily on days 0‡ and 3